Application of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane derivatives in asymmetric organocatalysis: the Biginelli reaction

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Application of SBA-Pr-SO3H as a solid acid nanoreactor in the Biginelli reaction

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Application of SBA-Pr-SO3H as a solid acid nanoreactor in the Biginelli reaction

Sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) with a pore size of 6 nm catalyzed three component coupling of aromatic aldehydes, urea and ethyl acetoacetate to afford the corresponding dihydropyrimidinones under solvent free condition. This new protocol for Biginelli reaction has important advantages such as green synthesis, short reaction time, easy isolation and high yields of ...

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ژورنال

عنوان ژورنال: Arkivoc

سال: 2008

ISSN: 1551-7012

DOI: 10.3998/ark.5550190.0009.606